Novel securinine derivatives as topoisomerase I based antitumor agents

Author:

Hou Wen,Wang Zhen-Ya,Peng Cheng-Kang,Lin Jing,Liu Xin,Chang Yi-Qun,Xu Jun,Jiang Ren-Wang,Lin Hui,Sun Ping-Hua,Chen Wei-MinORCID

Funder

Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference32 articles.

1. Selected novel flavones inhibit the DNA binding or the DNA religation step of eukaryotic topoisomerase I;Boege;J. Biol. Chem.,1996

2. The mechanism of topoisomerase I poisoning by a camptothecin analog;Staker;Proc. Natl. Acad. Sci.,2002

3. DNA topoisomerase I-mediated DNA cleavage and cytotoxicity of camptothecin analogs;Hsiang;Cancer Res,1989

4. Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: evidence for a special receptor site and a relation to antitumor activity;Jaxel;Cancer Res,1989

5. Progress of researching in antitumor drugs;Lin;Chin. J. Hosp. Pharm,1998

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