Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents
Author:
Funder
Deanship of Scientific Research
King Saud University
Ente Cassa di Risparmio di Firenze, Italy
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference70 articles.
1. Carbonic anhydrases: novel therapeutic applications for inhibitors and activators;Supuran;Nat. Rev. Drug Discov.,2008
2. Structure-based drug discovery of carbonic anhydrase inhibitors;Supuran;J. Enzym. Inhib. Med. Chem.,2012
3. How many carbonic anhydrase inhibition mechanisms exist?;Supuran;J. Enzym. Inhib. Med. Chem.,2016
4. Carbonic anhydrase inhibitors and activators for novel therapeutic applications;Supuran;Future Med. Chem.,2011
5. Antiglaucoma carbonic anhydrase inhibitors: a patent review;Masini;Expert Opin. Ther. Pat.,2013
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