Design, synthesis and pharmacological evaluation of a novel PEG-cRGD-conjugated irinotecan derivative as potential antitumor agent-Reference-Cited by-同舟云学术

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Design, synthesis and pharmacological evaluation of a novel PEG-cRGD-conjugated irinotecan derivative as potential antitumor agent

Published:2018-10 Issue: Volume:158 Page:82-90
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Huang Yang-Qing,Yuan Jian-Dong,Ding Hai-Feng,Song Yun-Song,Qian Gang,Wang Jia-Li,Ji Min,Zhang Ye^ORCID

Funder

National Natural Science Foundation of China

Innovative Team & Outstanding Talent Program of Colleges and Universities in Guangxi

Guangxi Natural Science Foundation

Ministry of Science and Technology of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference32 articles.

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2. A targeted approach to cancer imaging and therapy;Li;Nat. Mater.,2014

3. Theranostic nanoparticles with controlled release of gemcitabine for targeted therapy and MRI of pancreatic cancer;Lee;ACS Nano,2013

4. IGF1 receptor targeted theranostic nanoparticles for targeted and image-guided therapy of pancreatic cancer;Zhou;ACS Nano,2015

5. Irinotecan: mechanisms of tumor resistance and novel strategies for modulating its activity;Xu;Ann. Oncol.,2002

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1. A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers;npj Precision Oncology;2024-04-23

2. Discovery of two biotin-PEG4‑diarylidenyl piperidone prodrugs as potent antitumor agents with good efficacy, limited toxicity, and low resistance;Bioorganic Chemistry;2023-02

3. Synthesis, mechanisms of action, and toxicity of novel aminophosphonates derivatives conjugated irinotecan in vitro and in vivo as potent antitumor agents;European Journal of Medicinal Chemistry;2020-03

4. Design, synthesis and biological evaluation of naphthalenebenzimidizole platinum (II) complexes as potential antitumor agents;European Journal of Medicinal Chemistry;2020-02

5. Design, synthesis and antitumor activity of a novel PEG-A6-conjugated irinotecan derivative;Bioorganic & Medicinal Chemistry Letters;2020-01

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