Replacement of Arg with Nle and modified D-Phe in the core sequence of MSHs, Ac-His-D-Phe-Arg-Trp-NH2, leads to hMC1R selectivity and pigmentation
Author:
Funder
U.S. Public Health Service
National Institutes of Health
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference51 articles.
1. Increasing incidence of melanoma among middle-aged adults: an epidemiologic study in Olmsted County, Minnesota;Lowe;Mayo Clin. Proc.,2014
2. Quality of life in women with localised breast cancer or malignant melanoma 2 years after initial treatment: a comparison;Engel;Int. J. Behav. Med.,2014
3. Melanocortins as potential therapeutic agents in severe hypoxic conditions;Giuliani;Front. Neuroendocrinol.,2012
4. Is Mc1r an important regulator of non-pigmentary responses to UV radiation?;Zmijewski;Exp. Dermatol.,2013
5. Functional melanocortin 1 receptor Mc1r is not necessary for an inflammatory response to UV radiation in adult mouse skin;Wolnicka-Glubisz;Exp. Dermatol.,2013
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3. Ψ and χ Angle Constrains at the C-Terminus Trp Position of the Melanotropin Tetrapeptide Ac-His-d-Phe-Arg-Trp-NH2 Lead to Potent and Selective Agonists at hMC1R and hMC4R;Journal of Medicinal Chemistry;2023-05-03
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