Guanylthiourea derivatives as potential antimalarial agents: Synthesis, in vivo and molecular modelling studies

Author:

Bhagat Shweta,Arfeen Minhajul,Adane Legesse,Singh Savita,Singh Prati Pal,Chakraborti Asit K.,Bharatam Prasad V.

Funder

Department of Science and Technology, Government of India

University Grants Commission

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference42 articles.

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3. The dihydrofolate reductase domain of Plasmodium falciparum thymidylate synthase-dihydrofolate reductase. Gene synthesis, expression, and anti-folate-resistant mutants;Sirawaraporn;J. Biol. Chem.,1993

4. Mechanisms of resistance of malaria parasites to antifolates;Gregson;Pharmacol. Rev.,2005

5. Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria;Peterson;Proc. Natl. Acad. Sci. U. S. A.,1990

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