Synthesis of selective 11 β -HSD1 inhibitors based on dammarane scaffold-Reference-Cited by-同舟云学术

Synthesis of selective 11 β -HSD1 inhibitors based on dammarane scaffold

Published:2017-07 Issue: Volume:135 Page:324-338
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Shao Li-Dong^ORCID,Bao Ying,Shen Yu,Su Jia,Leng Ying,Zhao Qin-Shi^ORCID

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference24 articles.

1. Mechanisms linking obesity to insulin resistance and type 2 diabetes;Kahn;Nature,2006

2. Elevated hepatic 11β-hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia;Chapagain;Proc. Natl. Acad. Sci. U. S. A.,2014

3. Is 11β-hydroxysteroid dehydrogenase type 1 a therapeutic target? Effects of carbenoxolone in lean and obese zucker rats;Livingstone;J. Pharmacol. Exp. Ther.,2003

4. Carbenoxolone increases hepatic insulin sensitivity in man: a novel role for 11-oxosteroid reductase in enhancing glucocorticoid receptor activation;Walker;J. Clin. Endocrinol. Metab.,1995

5. Effects of the 11β-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes;Andrews;J. Clin. Endocrinol. Metab.,2003

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. One-Stage Pathway from Hollongdione to C17-Alkyne and Vinyl Chloride Following Mannich Bases and Carboxylic Acid;International Journal of Molecular Sciences;2024-07-30

2. Construction of an Epoxy-lactone Moiety on the C/D Ring of Highly Oxygenated Triterpenes through a Modified SeO2-Promoted Oxidative Cyclization;Synthesis;2023-07-04

3. Discovery and biological evaluation of tanshinone derivatives as potent dual inhibitors of indoleamine 2, 3-dioxygenase 1 and tryptophan 2, 3-dioxygenase;European Journal of Medicinal Chemistry;2022-05

4. Synthesis and Molecular Structure of Hydroxy and Hydroxyimino Derivatives of Hollongdione;Russian Journal of Organic Chemistry;2021-04

5. Newly synthesised oxime and lactone derivatives from Dipterocarpus alatus dipterocarpol as anti-diabetic inhibitors: experimental bioassay-based evidence and theoretical computation-based prediction;RSC Advances;2021