Pharmacophore guided discovery of small-molecule interleukin 15 inhibitors

Author:

Żyżyńska-Granica Barbara,Trzaskowski Bartosz,Niewieczerzał Szymon,Filipek Sławomir,Zegrocka-Stendel Oliwia,Dutkiewicz Małgorzata,Krzeczyński Piotr,Kowalewska Magdalena,Koziak Katarzyna

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference40 articles.

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2. Cloning of a T cell growth factor that interacts with the β chain of the interleukin-2 receptor;Grabstein;Science,1994

3. IL-15 an immunoregulatory and anti-cancer cytokine. Recent advances;Shanmugham;J. Exp. Clin. Cancer Res.,2006

4. Membrane bound IL-15 is increased on CD14 monocytes in early stages of MS;Vaknin-Dembinsky;J. Neuroimmunol.,2008

5. Role of IL-15, IL-2, and their receptors in the development of T cell alveolitis in pulmonary sarcoidosis;Agostini;J. Immunol.,1996

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