Pose, duplicate, then elaborate: Steps towards increased affinity for inhibitors targeting the specificity surface of the Pim-1 kinase
Author:
Funder
Helmholtz-Zentrum Berlin für Materialien und Energie
Deutsche Forschungsgemeinschaft
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
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3. Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc;Allen;Oncogene,1997
4. Proviral tagging in Eg-myc transgenic mice lacking the Pim-1 proto-oncogene leads to compensatory activation of Pim-2;van der Lugt;EMBO J.,1995
5. Evidence implicating Gfi-1 and Pim-1 in pre-T-cell differentiation steps associated with b-selection;Schmidt;EMBO J.,1997
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