Discovery of novel 5-methoxybenzothiophene hydrazides as metabolically stable Clk1 inhibitors with high potency and unprecedented Clk1 isoenzyme selectivity
Author:
Funder
Bundesministerium für Bildung und Forschung
DAAD
Deutscher Akademischer Austauschdienst
German University in Cairo
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
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3. SRPK1 and Clk/Sty protein kinases show distinct substrate specificities for serine/arginine-rich splicing factors;Colwill;J. Biol. Chem.,1996
4. Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation;Bullock;Structure,2009
5. In vivo regulation of alternative pre-mRNA splicing by the Clk1 protein kinase;Duncan;Mol. Cell Biol.,1997
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