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Design, synthesis, and biological evalution of bifunctional inhibitors against Hsp90-HDAC6 interplay

  • Published:2022-10 Issue: Volume:240 Page:114582
  • ISSN:0223-5234
  • Container-title:European Journal of Medicinal Chemistry
  • language:en
  • Short-container-title:European Journal of Medicinal Chemistry

Author:

Chae Hye Yun,Park Sun You,Jha Sonam,Gupta Sunil K.,Kim Mikyung,Ha Eunyoung,Seo Young Ho

Funder

Ministry of Education

National Research Foundation of Korea

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference53 articles.

1. Targeting HSP90 for cancer therapy;Mahalingam;Br. J. Cancer,2009

2. HSP90 and the chaperoning of cancer;Whitesell;Nat. Rev. Cancer,2005

3. Tumor selectivity of Hsp90 inhibitors: the explanation remains elusive;Chiosis;ACS Chem. Biol.,2006

4. Development and application of Hsp90 inhibitors;Solit;Drug Discov. Today,2008

5. Targeting the dynamic HSP90 complex in cancer;Trepel;Nat. Rev. Cancer,2010

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