Identification of novel Pyrrolo[2,3-d]Pyrimidine-based KRAS G12C inhibitors with anticancer effects
Author:
Funder
National Natural Science Foundation of China
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference35 articles.
1. A comprehensive survey of Ras mutations in cancer;Prior;Cancer Res.,2012
2. KRAS: feeding pancreatic cancer proliferation;Bryant;Trends Biochem. Sci.,2014
3. RAS oncogenes: weaving a tumorigenic web;Pylayeva-Gupta;Nat. Rev. Cancer,2011
4. Small-molecule inhibitors directly targeting KRAS as anticancer therapeutics;Chen;J. Med. Chem.,2020
5. RAS proteins and their regulators in human disease;Simanshu;Cell,2017
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