Discovery of novel 2,3-dihydro-1H-inden-1-ones as dual PDE4/AChE inhibitors with more potency against neuroinflammation for the treatment of Alzheimer's disease
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference38 articles.
1. Phosphodiesterase inhibitors for Alzheimer's disease: a systematic review of clinical trials and epidemiology with a mechanistic rationale;Sanders;J. Alzheimers Dis. Rep.,2020
2. The temporal trend and distribution characteristics in mortality of Alzheimer's disease and other forms of dementia in China: based on the National Mortality Surveillance System (NMS) from 2009 to 2015;Bo;PLoS One,2019
3. 2020 Alzheimer's disease facts and figures;Alzheimers Dement,2020
4. Alzheimer's disease and its treatment by different approaches: a review;Srivastava;Eur. J. Med. Chem.,2021
5. 2022 Alzheimer's disease facts and figures;AlzheimerAssociation;Alzheimers Dement,2022
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