Statins in therapy: Understanding their hydrophilicity, lipophilicity, binding to 3-hydroxy-3-methylglutaryl-CoA reductase, ability to cross the blood brain barrier and metabolic stability based on electrostatic molecular orbital studies-Reference-Cited by-同舟云学术

Statins in therapy: Understanding their hydrophilicity, lipophilicity, binding to 3-hydroxy-3-methylglutaryl-CoA reductase, ability to cross the blood brain barrier and metabolic stability based on electrostatic molecular orbital studies

Published:2014-10 Issue: Volume:85 Page:661-674
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Fong Clifford W.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference67 articles.

1. Pharmacological Actions of Statins: A Critical Appraisal in the Management of Cancer

2. Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update

3. Long-term use of rosuvastatin: a critical risk benefit appraisal and comparison with other antihyperlipidemics

4. The pleiotropic effects and therapeutic potential of the hydroxy-methyl-glutaryl-CoA reductase inhibitors in malignancies: A comprehensive review

5. Statins role in cancer prevention and development-recent meta-analyses

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