Synthesis, biological evaluation, in silico modeling and crystallization of novel small monocationic molecules with potent antiproliferative activity by dual mechanism
Author:
Funder
Ministerio de Innovación y Ciencia
Diamond Light Source
ARAID
MEC
Gobierno de Aragón
FEDER
FP7
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference38 articles.
1. Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion;Straussman;Nature,2012
2. A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: therapeutic targeting of tumor mitochondria with lipophilic cationic compounds;Kalyanaraman;Redox Biol,2018
3. Choline metabolism-based molecular diagnosis of cancer: an update;Glunde;Expert Rev. Mol. Diagn,2015
4. Molecular causes of elevated phosphoethanolamine in breast and pancreatic cancer cells;Shah;NMR Biomed.,2018
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