Design, synthesis, and evaluation of liver-specific gemcitabine prodrugs for potential treatment of hepatitis C virus infection and hepatocellular carcinoma

Author:

Stephenson Anthony A.,Cao Sheng,Taggart David J.,Vyavahare Vinod P.,Suo Zucai

Funder

Ohio State University

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference55 articles.

1. Assembly of infectious hepatitis C virus particles;Bartenschlager;Trends Microbiol.,2011

2. Global Hepatitis Report 2017,2017

3. Treatment of chronic hepatitis C: a systematic review;Chander;Hepatology,2002

4. Cancer statistics;Siegel;CA A Cancer J. Clin.,2015

5. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial;Burris;J. Clin. Oncol. : Off. J. Am. Soc. Clin. Oncol.,1997

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