Discovery of novel VX-809 hybrid derivatives as F508del-CFTR correctors by molecular modeling, chemical synthesis and biological assays-Reference-Cited by-同舟云学术

Discovery of novel VX-809 hybrid derivatives as F508del-CFTR correctors by molecular modeling, chemical synthesis and biological assays

Published:2020-12 Issue: Volume:208 Page:112833
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Parodi Alice^ORCID,Righetti Giada,Pesce Emanuela,Salis Annalisa,Tasso Bruno^ORCID,Urbinati Chiara^ORCID,Tomati Valeria,Damonte Gianluca,Rusnati Marco^ORCID,Pedemonte Nicoletta,Cichero Elena,Millo Enrico

Funder

Fondazione Italiana Fibrosi Cistica

Italian Ministry of Health

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference46 articles.

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5. Impact of the F508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure;Lewis;J. Biol. Chem.,2005

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