Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitors

Author:

Matheson Christopher J.,Casalvieri Kimberly A.,Backos Donald S.,Minhajuddin Mohammed,Jordan Craig T.,Reigan Philip

Funder

NIH

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference80 articles.

1. AMPK: a nutrient and energy sensor that maintains energy homeostasis;Hardie;Nat. Rev. Mol. Cell Biol.,2012

2. AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer;Hardie;Biochem. Soc. Trans.,2011

3. The LKB1-AMPK pathway: metabolism and growth control in tumour suppression;Shackelford;Nat. Rev. Canc.,2009

4. Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase;Hawley;Cell Metabol.,2005

5. Activation of GLUT1 by metabolic and osmotic stress: potential involvement of AMP-activated protein kinase (AMPK);Barnes;J. Cell Sci.,2002

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