Automated design and optimization of multitarget schizophrenia drug candidates by deep learning-Reference-Cited by-同舟云学术

Automated design and optimization of multitarget schizophrenia drug candidates by deep learning

Published:2020-10 Issue: Volume:204 Page:112572
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Tan Xiaoqin,Jiang Xiangrui,He Yang,Zhong Feisheng,Li Xutong,Xiong Zhaoping^ORCID,Li Zhaojun,Liu Xiaohong,Cui Chen,Zhao Qingjie,Xie Yuanchao,Yang Feipu,Wu Chunhui,Shen Jingshan,Zheng Mingyue,Wang Zhen,Jiang Hualiang

Funder

National Natural Science Foundation of China

Key New Drug Creation and Manufacturing Program

Personalized Medicines—Molecular Signature-based Drug Discovery and Development

Chinese Academy of Sciences

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference60 articles.

1. Schizophrenia: treatment targets beyond monoamine systems;Ibrahim;Annu. Rev. Pharmacol. Toxicol.,2011

2. Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia;Roth;Nat. Rev. Drug Discov.,2004

3. Schizophrenia, “just the facts” 4. Clinical features and conceptualization;Tandon;Schizophr. Res.,2009

4. Drug treatment of schizophrenia: overview of recent research;Marder;Schizophr. Res.,1991

5. Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents;Miyamoto;Mol. Psychiatr.,2012

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. AI for targeted polypharmacology: The next frontier in drug discovery;Current Opinion in Structural Biology;2024-02

2. ChemSpaceAL: An Efficient Active Learning Methodology Applied to Protein-Specific Molecular Generation;Journal of Chemical Information and Modeling;2024-01-30

3. Artificial intelligence systems for the design of magic shotgun drugs;Artificial Intelligence in the Life Sciences;2023-12

4. Efficient 3D Molecular Design with an E(3) Invariant Transformer VAE;The Journal of Physical Chemistry A;2023-09-05

5. Ruthenium complexes for breast cancer therapy;Reviews in Inorganic Chemistry;2023-07-28