Design and structural optimization of novel 2H-benzo[h]chromene derivatives that target AcrB and reverse bacterial multidrug resistance-Reference-Cited by-同舟云学术

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Design and structural optimization of novel 2H-benzo[h]chromene derivatives that target AcrB and reverse bacterial multidrug resistance

Published:2021-03 Issue: Volume:213 Page:113049
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Wang Yinhu,Alenazy Rawaf,Gu Xinjie,Polyak Steven W.^ORCID,Zhang Panpan,Sykes Matthew J.,Zhang Na,Venter Henrietta,Ma Shutao^ORCID

Funder

Major Scientific and Technological Innovation Project of Shandong Province

Science and Technology Development Plan of Shandong Province

National Natural Science Foundation of China

National Health and Medical Research Council

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference39 articles.

1. Multiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition;Zwama;Nat. Commun.,2018

2. The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria;Li;Clin. Microbiol. Rev.,2015

3. Waltzing transporters and ’the dance macabre’ between humans and bacteria;Lomovskaya;Nat. Rev. Drug Discov.,2007

4. Multiple molecular mechanisms for multidrug resistance transporters;Higgins;Nature,2007

5. Activity of Zanthoxylum clava-herculis extracts against multi-drug resistant methicillin-resistant Staphylococcus aureus (mdr-MRSA);Gibbons;Phytother. Res.,2003

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1. Eco-friendly Approaches to Chromene Derivatives: A Comprehensive Review of Green Synthesis Strategies;Current Topics in Medicinal Chemistry;2024-08-06

2. Targeted potent antimicrobial and antitumor oxygen-heterocyclic-based pyran analogues: synthesis and computational studies;Scientific Reports;2024-04-29

3. Extending the Potency and Lifespan of Antibiotics: Inhibitors of Gram-Negative Bacterial Efflux Pumps;ACS Infectious Diseases;2024-04-25

4. Required criteria of drug efflux pump inhibitors to disrupt the function of AcrB subunit protein from AcrAB-TolC multidrug efflux pump from Escherichia coli;Journal of King Saud University - Science;2024-04

5. Comparative reassessment of AcrB efflux inhibitors reveals differential impact of specific pump mutations on the activity of potent compounds;Microbiology Spectrum;2024-02-06

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