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Capsaicin derivatives with nitrothiophene substituents: Design, synthesis and antibacterial activity against multidrug-resistant S. aureus

  • Published:2020-07 Issue: Volume:198 Page:112352
  • ISSN:0223-5234
  • Container-title:European Journal of Medicinal Chemistry
  • language:en
  • Short-container-title:European Journal of Medicinal Chemistry

Author:

Wang Zhi-Cheng,Wei Bingyan,Pei Fang-Ning,Yang Teng,Tang Jie,Yang Song,Yu Li-Fang,Yang Cai-Guang,Yang Fan

Funder

the National Key Technology R&D Program

National Natural Science Foundation of China

the Science and Technology Commission Shanghai Municipality

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference31 articles.

1. Waves of resistance: Staphylococcus aureus in the antibiotic era;Chambers;Nat. Rev. Microbiol.,2009

2. Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis;Tacconelli;Lancet Infect. Dis.,2018

3. Chemical intervention on Staphylococcus aureus virulence;Zhou;Chin. J. Chem.,2019

4. In vitro activity of capsaicin against Helicobacter pylori;Zeyrek;Ann. Microbiol.,2005

5. Antibacterial activity of capsaicin against sectional cariogenic bacteria;Gu;Pakistan J. Zool.,2019

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