Design, synthesis and structure-based optimization of novel isoxazole-containing benzamide derivatives as FtsZ modulators-Reference-Cited by-同舟云学术

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Design, synthesis and structure-based optimization of novel isoxazole-containing benzamide derivatives as FtsZ modulators

Published:2018-11 Issue: Volume:159 Page:90-103
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Bi Fangchao,Song Di,Zhang Nan,Liu Zhiyang^ORCID,Gu Xinjie,Hu Chaoyu,Cai Xiaokang,Venter Henrietta,Ma Shutao

Funder

National Natural Science Foundation of China

Major Project of Research and Development of Shandong Province

Key Research and Development Project of Shandong Province

Major Project of Science and Technology of Shandong Province

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference39 articles.

1. Anti-virulence strategies to combat bacteria-mediated disease;Rasko;Nat. Rev. Drug Discov.,2010

2. Targeting the bacterial division protein FtsZ;Hurley;J. Med. Chem.,2016

3. Cell-division inhibitors: new insights for future antibiotics;Lock;Nat. Rev. Drug Discov.,2008

4. The development of FtsZ inhibitors as potential antibacterial agents;Ma;ChemMedChem,2012

5. Targeting the assembly of bacterial cell division protein FtsZ with small molecules;Schaffner-Barbero;ACS Chem. Biol.,2012

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1. T5S1607 identified as a antibacterial FtsZ inhibitor：Virtual screening combined with bioactivity evaluation for the drug discovery;Computational Biology and Chemistry;2024-02

2. New broad-spectrum and potent antibacterial agents with dual-targeting mechanism: Promoting FtsZ polymerization and disrupting bacterial membranes;European Journal of Medicinal Chemistry;2024-01

3. Design of novel water-soluble isoxazole-based antimicrobial agents and evaluation of their cytotoxicity and acute toxicity;Bioorganic Chemistry;2023-09

4. Effective Synthesis and Anti‐Mycobacterial Activity of Isoxazole‐Substituted Piperazine Derivatives;ChemistrySelect;2023-05-08

5. Structural Variations in the Central Heterocyclic Scaffold of Tripartite 2,6-Difluorobenzamides: Influence on Their Antibacterial Activity against MDR Staphylococcus aureus;Molecules;2022-10-05

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