Synthesis and biological evaluation of dihydroquinazoline-2-amines as potent non-nucleoside reverse transcriptase inhibitors of wild-type and mutant HIV-1 strains-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of dihydroquinazoline-2-amines as potent non-nucleoside reverse transcriptase inhibitors of wild-type and mutant HIV-1 strains

Published:2019-08 Issue: Volume:176 Page:11-20
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Jin KaiJun,Sang YaLi,Han Sheng,De Clercq Erik,Pannecouque Christophe,Meng Ge,Chen FenEr

Funder

National Natural Science Foundation of P. R. China

Shanghai Municipal Natural Science Foundation

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference31 articles.

1. Allosteric suppression of HIV-1 reverse transcriptase structural dynamics upon inhibitor binding;Seckler;Biophys. J.,2011

2. Nucleoside and nucleotide HIV reverse transcriptase inhibitors: 25 years after zidovudine;Cihlar;Antivir. Res.,2010

3. Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: a review of the last 20 years (1989-2009);de Béthune;Antivir. Res.,2010

4. Structural basis for drug resistance mechanisms for non-nucleoside inhibitors of HIV reverse transcriptase;Ren;Virus Res.,2008

5. Efavirenz a nonnucleoside reversetranscriptase inhibitor of first-generation: approaches based on its medicinal chemistry;Bastos;Eur. J. Med. Chem.,2016

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Deciphering the enigmas of non‐nucleoside reverse transcriptase inhibitors (NNRTIs): A medicinal chemistry expedition towards combating HIV drug resistance;Medicinal Research Reviews;2024-08-26

2. Challenges in designing antiviral agents;Viral Infections and Antiviral Therapies;2023

3. Current scenario on non-nucleoside reverse transcriptase inhibitors (2018-present);Arabian Journal of Chemistry;2022-12

4. Natural products and synthetic analogues against HIV: A perspective to develop new potential anti-HIV drugs;European Journal of Medicinal Chemistry;2022-04

5. New efficient synthesis of polysubstituted 3,4-dihydroquinazolines and 4H-3,1-benzothiazines through a Passerini/Staudinger/aza-Wittig/addition/nucleophilic substitution sequence;Beilstein Journal of Organic Chemistry;2022-03-04