Discovery of tropinone-thiazole derivatives as potent caspase 3/7 activators, and noncompetitive tyrosinase inhibitors with high antiproliferative activity: Rational design, one-pot tricomponent synthesis, and lipophilicity determination
Author:
Funder
Nicolaus Copernicus University
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference28 articles.
1. Global Cancer Statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries;Bray;Ca - Cancer J. Clin.,2018
2. Tropane alkaloids: chemistry, pharmacology, biosynthesis and production;Kohnen-Johannsen;Molecules,2019
3. Tropane alkaloids as medicinally useful natural products and their synthetic derivatives as new drugs;Grynkiewicz;Pharmacol. Rep.,2008
4. Tropinone synthesis via an atypical polyketide synthase and P450-mediated cyclization;Bedewitz;Nat. Commun.,2018
Cited by 40 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Synthesis of novel star-shaped molecules based on a pentaerythritol core linked to different heterocyclic systems;Results in Chemistry;2024-08
2. Synthesis and Anti‐Bacterial Evaluation of Novel Scaffolds Based on Bis‐Thiazole or bis‐1,3,4‐Thiadiazole Linked to Thieno[2,3‐b]Thiophene as New Hybrid Molecules;ChemistrySelect;2024-04-09
3. Synthesis of naproxen thiadiazole urea hybrids and determination of their anti-melanoma, anti-migration, tyrosinase inhibitory activity, and molecular docking studies;Journal of Molecular Structure;2024-01
4. The patent review of the biological activity of tropane containing compounds;Expert Opinion on Therapeutic Patents;2023-12-02
5. Alkaloids as Additional Weapons in the Fight against Breast Cancer: A review;Current Medicinal Chemistry;2023-09-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3