Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease
Author:
Funder
University of Bari
MIUR, Italy
RUDN 5–100
RFBR
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference67 articles.
1. A review on Alzheimer's disease pathophysiology and its management: an update;Kumar;Pharmacol. Rep.,2015
2. Protein misfolding, amyloid formation, and human disease: a summary of progress over the last decade;Chiti;Annu. Rev. Biochem.,2017
3. Pharmacotherapy of Alzheimer's disease: current and future trends;Geldenhuys;Expert Rev. Neurother.,2015
4. Structure, activities and biomedical applications of human butyrylcholinesterase;Masson;Protein Pept. Lett.,2009
5. Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer β-amyloid peptide in rodent;Greig;Proc. Natl. Acad. Sci. U.S.A.,2005
Cited by 52 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Chiral thioureas containing naphthalene moiety as selective butyrylcholinesterase inhibitors: Design, synthesis, cholinesterase inhibition activity and molecular docking studies;Journal of Molecular Structure;2025-01
2. Chiral pyrrolidines as multipotent agents in Alzheimer and neurodegenerative diseases;Bioorganic & Medicinal Chemistry;2024-08
3. Spectroscopic characterization, quantum chemical and molecular docking investigations on methyl indole-3-carboxylate: A potent cervical cancer drug;Journal of Molecular Structure;2024-06
4. The selective butyrylcholinesterase inhibitor UW‐MD‐95 shows symptomatic and neuroprotective effects in a pharmacological mouse model of Alzheimer's disease;CNS Neuroscience & Therapeutics;2024-06
5. Indole-Based Compounds in the Development of Anti-Neurodegenerative Agents;Molecules;2024-05-03
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3