Lead identification of conformationally restricted β-lactam type combretastatin analogues: Synthesis, antiproliferative activity and tubulin targeting effects
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference47 articles.
1. Tubulin and microtubule structure;Downing;Curr. Opin. Cell Biol.,1998
2. Mechanism of action of antitumor drugs that interact with microtubules and tubulin;Jordan;Curr. Med. Chem. Anticancer Agents,2002
3. Microtubules as a target for anticancer drugs;Jordan;Nat. Rev. Cancer,2004
4. Tubulin and microtubules as targets for anticancer drugs;Hadfield;Prog. Cell Cycle Res.,2003
5. Mechanism of colchicine-dimer addition to microtubule ends: implications for the microtubule polymerization mechanism;Margolis;Biochemistry,1980
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