Hydrogen peroxide activated quinone methide precursors with enhanced DNA cross-linking capability and cytotoxicity towards cancer cells-Reference-Cited by-同舟云学术

Hydrogen peroxide activated quinone methide precursors with enhanced DNA cross-linking capability and cytotoxicity towards cancer cells

Published:2017-06 Issue: Volume:133 Page:197-207
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Wang Yibin,Fan Heli,Balakrishnan Kumudha,Lin Zechao,Cao Sheng,Chen Wenbing,Fan Yukai,Guthrie Quibria A.,Sun Huabing,Teske Kelly A.,Gandhi Varsha,Arnold Leggy A.,Peng Xiaohua

Funder

National Institutes of Health

Great Milwaukee Foundation (Shaw Scientist Award)

University of Wisconsin Milwaukee Research Growth Initiative

University of Wisconsin Milwaukee Research Foundation (Catalyst grant)

Lynde and Harry Bradley Foundation

Richard and Ethel Herzfeld Foundation

Wisconsin Applied Research Grant (ARG) Award

CLL Global Research Foundation

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference46 articles.

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5. Toward hypoxia-selective DNA-alkylating agents built by grafting nitrogen mustards onto the bioreductively activated, hypoxia-selective DNA-oxidizing agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine);Johnson;J. Org. Chem.,2014

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