Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase-Reference-Cited by-同舟云学术

Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase

Published:2017-06 Issue: Volume:133 Page:85-96
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Tang Jing,Vernekar Sanjeev Kumar V.,Chen Yue-Lei,Miller Lena,Huber Andrew D.,Myshakina Nataliya,Sarafianos Stefan G.,Parniak Michael A.,Wang Zhengqiang^ORCID

Funder

National Institutes of Health

University of Minnesota

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference33 articles.

1. HIV-1 replication, Somat;Freed;Cell Mol. Genet.,2001

2. Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the Use of Antiretroviral Agents in HIV-1-infected Adults and Adolescents;D.o.H.a.H. Services,2015

3. Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition;Sarafianos;J. Mol. Biol.,2009

4. Nucleoside and nucleotide HIV reverse transcriptase inhibitors: 25 years after zidovudine;Cihlar;Antivir. Res.,2010

5. Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: a review of the last 20 years (1989-2009);de Bethune;Antivir. Res.,2010

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Inhibiting HCMV pUL89-C Endonuclease with Metal-Binding Compounds;Journal of Medicinal Chemistry;2023-10-12

2. Quinolines and isoquinolines as HIV-1 inhibitors: Chemical structures, action targets, and biological activities;Bioorganic Chemistry;2023-07

3. Recent advances on dual inhibitors targeting HIV reverse transcriptase associated polymerase and ribonuclease H;European Journal of Medicinal Chemistry;2023-03

4. Repurposing N-hydroxy thienopyrimidine-2,4-diones (HtPD) as inhibitors of human cytomegalovirus pUL89 endonuclease: Synthesis and biological characterization;Bioorganic Chemistry;2022-12

5. Current medicinal chemistry strategies in the discovery of novel HIV-1 ribonuclease H inhibitors;European Journal of Medicinal Chemistry;2022-12