Design, synthesis and receptor affinity of novel conformationally restricted σ ligands based on the [4.3.3]propellane scaffold-Reference-Cited by-同舟云学术

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Design, synthesis and receptor affinity of novel conformationally restricted σ ligands based on the [4.3.3]propellane scaffold

Published:2013-12 Issue: Volume:70 Page:78-87
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Torres-Gómez Héctor,Lehmkuhl Kirstin,Schepmann Dirk,Wünsch Bernhard

Funder

Government of the State Nordrhein-Westfalen

Westfälische Wilhelms-Universität Münster

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference52 articles.

1. Classification and nomenclature of phencyclidine and sigma receptor sites

2. Sigma receptors: biology and therapeutic potential

3. σ-Receptors in Endocrine Organs: Identification, Characterization, and Autoradiographic Localization in Rat Pituitary, Adrenal, Testis, and Ovary

4. Purification, molecular cloning, and expression of the mammalian sigma1-binding site.

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1. Synthesis of dioxapropellanes using Mn(III)-based oxidative tandem cyclization of tetracarbonyl compounds with diarylethenes;Bulletin of the Chemical Society of Japan;2024-01-29

2. Chemically Recyclable Poly(β-thioether ester)s Based on Rigid Spirocyclic Ketal Diols Derived from Citric Acid;Biomacromolecules;2022-05-26

3. Molecular Iodine-Mediated Synthesis of 2-Azaanthraquinones from [3.3.3]Propellanes via a Metal-Free Rearrangement;Synthesis;2021-07-21

4. Propellanes as Rigid Scaffolds for the Stereodefined Attachment of σ-Pharmacophoric Structural Elements to Achieve σ Affinity;International Journal of Molecular Sciences;2021-05-26

5. Synthesis of 3-aza[4.4.3]propellanes with high σ1 receptor affinity;Bioorganic & Medicinal Chemistry;2018-05

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