Design, synthesis, and biological evaluation of novel 2-ethyl-5-phenylthiazole-4-carboxamide derivatives as protein tyrosine phosphatase 1B inhibitors with improved cellular efficacy-Reference-Cited by-同舟云学术

Design, synthesis, and biological evaluation of novel 2-ethyl-5-phenylthiazole-4-carboxamide derivatives as protein tyrosine phosphatase 1B inhibitors with improved cellular efficacy

Published:2013-11 Issue: Volume:69 Page:399-412
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Chen Yue-Ting,Tang Chun-Lan,Ma Wei-Ping,Gao Li-Xin,Wei Yi,Zhang Wei,Li Jing-Ya,Li Jia,Nan Fa-Jun

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference45 articles.

1. The emerging science of body weight regulation and its impact on obesity treatment;Korner;J. Clin. Invest.,2003

2. Osmotic loading of neutralizing antibodies demonstrates a role for protein-tyrosine phosphatase 1B in negative regulation of the insulin action pathway;Ahmad;J. Biol. Chem.,1995

3. PTP1B: a double agent in metabolism and oncogenesis;Yip;Trends Biochem. Sci.,2010

4. In control at the ER: PTP1B and the down-regulation of RTKs by dephosphorylation and endocytosis;Stuible;Trends Cell Biol.,2010

5. Protein tyrosine phosphatase 1B negatively regulates leptin signaling in a hypothalamic cell line;Kaszubska;Mol. Cell. Endocrinol.,2002

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