Discovery of a potent p38α/MAPK14 kinase inhibitor: Synthesis, in vitro/in vivo biological evaluation, and docking studies-Reference-Cited by-同舟云学术

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Discovery of a potent p38α/MAPK14 kinase inhibitor: Synthesis, in vitro/in vivo biological evaluation, and docking studies

Published:2019-12 Issue: Volume:183 Page:111684
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

El-Gamal Mohammed I.,Anbar Hanan S.,Tarazi Hamadeh,Oh Chang-Hyun

Funder

Korea Institute of Science and Technology (KIST, Seoul, Republic of Korea), KIST

University of Sharjah (Drug Design & Discovery Research Group Operational Fund), United Arab Emirates

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference39 articles.

1. p38 Mitogen-Activated Protein Kinase (MAPK) in Rheumatoid Arthritis

2. The p38 mitogen-activated protein kinase (MAPK) pathway in rheumatoid arthritis

3. Selective p38α Inhibitors Clinically Evaluated for the Treatment of Chronic Inflammatory Disorders

4. The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation

5. SB202190, a selective inhibitor of p38 mitogen-activated protein kinase, is a powerful regulator of LPS-induced mRNAs in monocytes

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1. Sodium Propionate Relieves LPS-Induced Inflammation by Suppressing the NF-ĸB and MAPK Signaling Pathways in Rumen Epithelial Cells of Holstein Cows;Toxins;2023-07-03

2. Evaluation of Substituted Pyrazole-Based Kinase Inhibitors in One Decade (2011–2020): Current Status and Future Prospects;Molecules;2022-01-05

3. LncRNA XIST knockdown alleviates LPS-induced acute lung injury by inactivation of XIST/miR-132-3p/MAPK14 pathway;Molecular and Cellular Biochemistry;2021-08-03

4. Polypharmacology of Gongronema latifolium leaf secondary metabolites against protein kinases implicated in Parkinson's disease and Alzheimer's disease;Scientific African;2021-07

5. The p38 MAPK Inhibitors and Their Role in Inflammatory Diseases;ChemistrySelect;2021-06-17

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