Structure-based virtual screening and biological evaluation of novel non-bisphosphonate farnesyl pyrophosphate synthase inhibitors-Reference-Cited by-同舟云学术

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Structure-based virtual screening and biological evaluation of novel non-bisphosphonate farnesyl pyrophosphate synthase inhibitors

Published:2020-01 Issue: Volume:186 Page:111905
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Liu Qingzhu,Miao Yinxing,Wang Xiaodan,Lv Gaochao,Peng Ying,Li Ke,Li Ming,Qiu Ling,Lin Jianguo^ORCID

Funder

Wuxi Commission of Health and Family Planning

Jiangsu Institute of Nuclear Medicine

Natural Science Foundation of Jiangsu Province

Jiangsu Province

Jiangsu Provincial Medical Youth Talent

Precision Medical Project of Wuxi Commission of Health and Family Planning

Chinese Academy of Agricultural Sciences

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference54 articles.

1. Chemical approaches to inhibitors of isoprenoid biosynthesis targeting farnesyl and geranylgeranyl pyrophosphate synthases;Merino;RSC Adv.,2017

2. Isoprenoids and protein prenylation: implications in the pathogenesis and therapeutic intervention of Alzheimer’s disease;Jeong;Crit. Rev. Biochem. Mol. Biol.,2018

3. The interplay between cell signalling and the mevalonate pathway in cancer;Mullen;Nat. Rev. Cancer,2016

4. Mevalonate pathway and human cancers;Bathaie;Curr. Mol. Pharmacol.,2017

5. FPPS mediates TGF-beta1-induced non-small cell lung cancer cell invasion and the EMT process via the RhoA/Rock 1 pathway;Lin;Biochem. Biophys. Res. Co.,2018

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3. Inhibition of zoledronic acid derivatives with extended methylene linkers on osteoclastogenesis involve downregulation of JNK and Akt pathways;Cell Biology International;2021-01-21

4. Pharmacological evaluation of imidazole‐derived bisphosphonates on receptor activator of nuclear factor‐κB ligand‐induced osteoclast differentiation and function;Chemical Biology & Drug Design;2020-08-06

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