Design, synthesis and biological evaluation of N-(3-(1H-tetrazol-1-yl)phenyl)isonicotinamide derivatives as novel xanthine oxidase inhibitors-Reference-Cited by-同舟云学术

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Design, synthesis and biological evaluation of N-(3-(1H-tetrazol-1-yl)phenyl)isonicotinamide derivatives as novel xanthine oxidase inhibitors

Published:2019-12 Issue: Volume:183 Page:111717
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Zhang Ting-jian,Zhang Yi,Tu Shun,Wu Yu-hang,Zhang Zhen-hao,Meng Fan-hao

Funder

National Natural Science Foundation of China

Scientific Research Fund of Liaoning Provincial Education Department

Doctoral Research Funding

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference47 articles.

1. Inhibitors of xanthine oxidase: scaffold diversity and structure-based drug design;Luna;ChemMedChem,2019

2. Xanthine oxidase inhibitory properties and anti-inflammatory activity of 2-amino-5-alkylidene-thiazol-4-ones;Smelcerovic;Chem. Biol. Interact.,2015

3. Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted pharmacokinetics and toxicity;Šmelcerović;Eur. J. Med. Chem.,2017

4. 9-Benzoyl 9-deazaguanines as potent xanthine oxidase inhibitors;Rodrigues;Bioorg. Med. Chem.,2016

5. 3,4-Dihydroxy-5-nitrobenzaldehyde (DHNB) is a potent inhibitor of xanthine oxidase: a potential therapeutic agent for treatment of hyperuricemia and gout;Lü;Biochem. Pharmacol.,2013

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