Ligand binding studies, preliminary structure–activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inhibitors of Escherichia coli dihydrofolate reductase-Reference-Cited by-同舟云学术

Ligand binding studies, preliminary structure–activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inhibitors of Escherichia coli dihydrofolate reductase

Published:2015-10 Issue: Volume:103 Page:600-614
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Srinivasan Bharath^ORCID,Tonddast-Navaei Sam^ORCID,Skolnick Jeffrey

Funder

Division of General Medical Sciences of the NIH

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference65 articles.

1. Multidrug efflux pumps of gram-negative bacteria;Nikaido;J. Bacteriol.,1996

2. Resistance in gram-negative bacteria: Enterobacteriaceae;Paterson;Am. J. Infect. Control,2006

3. Antibiotic-supersusceptible mutants of Escherichia coli and Salmonella typhimurium;Vaara;Antimicrob. Agents Chemother.,1993

4. Economic burden associated with multi-resistant Gram-negative organisms compared with that for methicillin-resistant Staphylococcus aureus in a university teaching hospital;Daxboeck;J. Hosp. Infect.,2006

5. Antibiotics and bacterial resistance in the 21st century;Fair;Perspect. Med. Chem.,2014

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, synthesis, biological evaluation and molecular docking of cyclic biguanidine compounds as cholinesterase inhibitors;Journal of Biomolecular Structure and Dynamics;2022-12-20

2. Recent Design and Structure-Activity Relationship Studies on the Modifications of DHFR Inhibitors as Anticancer Agents;Current Medicinal Chemistry;2021-04-01

3. Quinoline: A Promising Scaffold in Recent Antiprotozoal Drug Discovery;ChemistrySelect;2021-03

4. Design, synthesis and evaluation of carbazole derivatives as potential antimicrobial agents;Journal of Enzyme Inhibition and Medicinal Chemistry;2021-01-01

5. Dihydrofolate reductase inhibitors for use as antimicrobial agents;European Journal of Medicinal Chemistry;2020-06