Design, synthesis, docking studies and biological evaluation of novel dihydro-1,3,5-triazines as human DHFR inhibitors
Author:
Funder
Natural Science Foundation of Shanghai
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference32 articles.
1. The renewed potential for folate antagonists in contemporary cancer chemotherapy;Berman;J. Med. Chem.,1991
2. Design and synthesis of small molecular dual inhibitor of falcipain-2 and dihydrofolate reductase as antimalarial agent;Huang;Bioorg. Med. Chem. Lett.,2011
3. Dna and rna synthesis: antifolates;Kompis;Chem. Rev.,2005
4. Recent advances in classical and non-classical antifolates as antitumor and antiopportunistic infection agents: part ii;Gangjee;Anti-cancer agents Med. Chem.,2007
5. Deaza analogs of folic acid as antitumor agents;Kisliuk;Curr. Pharm. Des.,2003
Cited by 28 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. 1,3,5-Triazine as a promising scaffold in the development of therapeutic agents against breast cancer;European Journal of Medicinal Chemistry;2024-10
2. Effects of solvent casted poly (lactic acid)/poly(ethylene glycol)/paraben derivative triazine films on antibacterial performance and cytotoxicity;Polymers for Advanced Technologies;2024-03
3. Dihydrofolate Reductase (DHFR) Inhibitors: A Comprehensive Review;Current Medicinal Chemistry;2024-02
4. Dihydrofolate Reductase Inhibitors as Anticancer Agents: Progress and Perspectives in Drug Design and Development;Interdisciplinary Cancer Research;2024
5. Membrane-active substituted triazines as antibacterial agents against Staphylococcus aureus with potential for low drug resistance and broad activity;European Journal of Medicinal Chemistry;2023-10
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3