Treatment of estrogen-dependent diseases: Design, synthesis and profiling of a selective 17β-HSD1 inhibitor with sub-nanomolar IC 50 for a proof-of-principle study-Reference-Cited by-同舟云学术

Treatment of estrogen-dependent diseases: Design, synthesis and profiling of a selective 17β-HSD1 inhibitor with sub-nanomolar IC 50 for a proof-of-principle study

Published:2017-02 Issue: Volume:127 Page:944-957
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Abdelsamie Ahmed S.,van Koppen Chris J.,Bey Emmanuel,Salah Mohamed,Börger Carsten,Siebenbürger Lorenz,Laschke Matthias W.,Menger Michael D.,Frotscher Martin

Funder

Egyptian Ministry of Higher Education and Scientific Research

Deutscher Akademischer Austauschdienst

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference38 articles.

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3. 17β-hydroxysteroid dehydrogenase enzymes and breast cancer;Jansson;J. Steroid Biochem. Mol. Biol.,2009

4. Androgenic and estrogenic 17β-hydroxysteroid dehydrogenase/17-ketosteroid reductase in human ovarian epithelial tumors: evidence for the type 1, 2 and 5 isoforms;Blomquist;J. Steroid Biochem. Mol. Biol.,2002

5. Molecular endocrinology of hydroxysteroid dehydrogenases;Penning;Endocr. Rev.,1997

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