Computer aided drug discovery of highly ligand efficient, low molecular weight imidazopyridine analogs as FLT3 inhibitors-Reference-Cited by-同舟云学术

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Computer aided drug discovery of highly ligand efficient, low molecular weight imidazopyridine analogs as FLT3 inhibitors

Published:2015-04 Issue: Volume:94 Page:123-131
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Frett Brendan,McConnell Nick,Smith Catherine C.,Wang Yuanxiang,Shah Neil P.,Li Hong-yu

Funder

The National Institutes of Health

National Cancer Institute to N.P.S

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference42 articles.

1. Targeting the FMS-like tyrosine kinase 3 in acute myeloid leukemia;Swords;Leukemia,2012

2. c-Kit ligand and Flt3 ligand: stem/progenitor cell factors with overlapping yet distinct activities;Lyman;Blood,1998

3. A FLT3-targeted tyrosine kinase inhibitor is cytotoxic to leukemia cells in vitro and in vivo;Levis;Blood,2002

4. Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia;Meshinchi;Blood,2001

5. Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product;Kiyoi;Leukemia,1998

Cited by 25 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. N-(3-Methoxyphenyl)-6-(7-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl)pyridin-2-amine is an inhibitor of the FLT3-ITD and BCR-ABL pathways, and potently inhibits FLT3-ITD/D835Y and FLT3-ITD/F691L secondary mutants;Bioorganic Chemistry;2024-02

2. An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L;European Journal of Medicinal Chemistry;2024-01

3. Novel sulfonamides unveiled as potent anti-lung cancer agents via tumor pyruvate kinase M2 activation;RSC Medicinal Chemistry;2024

4. Imidazopyridine-based kinase inhibitors as potential anticancer agents: A review;Bioorganic Chemistry;2023-11

5. Fused Pyridine Derivatives: Synthesis and Biological Activities;Exploring Chemistry with Pyridine Derivatives;2023-01-04

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