Discovery of new indomethacin-based analogs with potentially selective cyclooxygenase-2 inhibition and observed diminishing to PGE2 activities
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference35 articles.
1. Structure of prostaglandin H2 synthase-1 (COX-1) and its NSAID binding sites;Loll,1996
2. Coxibs interfere with the action of aspirin by binding tightly to one monomer of cyclooxygenase-1;Rimon;Proc. Natl. Acad. Sci. U. S. A.,2010
3. Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation;Vane;Proc. Natl. Acad. Sci. U. S. A.,1994
4. Cyclooxygenase in normal human tissues is COX-1 really a constitutive isoform, and COX-2 an inducible isoform?;Zidar;J. Cell. Mol. Med.,2009
5. Differential COX-2 induction by viral and bacterial PAMPs: consequences for cytokine and interferon responses and implications for anti-viral COX-2 directed therapies;Kirkby;Biochem. Biophys. Res. Commun.,2013
Cited by 22 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Identification of New Potential Cyclooxygenase-2 Inhibitors Using Structure-Based Virtual Screening, Molecular Dynamics and Pharmacokinetic Modelling;IECBM 2024;2024-09-06
2. Indomethacin Derivatives as Potential Anticancer Agents ‐ Daybreak of New Epoch;ChemistrySelect;2024-08-08
3. Synthesis, Docking, and DFT Studies on Novel Schiff Base Sulfonamide Analogues as Selective COX-1 Inhibitors with Anti-Platelet Aggregation Activity;Pharmaceuticals;2024-05-30
4. Supramolecular nanofiber of indomethacin derivative confers highly cyclooxygenase-2 (COX-2) selectivity and boosts anti-inflammatory efficacy;Journal of Controlled Release;2023-12
5. Synthesis of new multitarget-directed ligands containing thienopyrimidine nucleus for inhibition of 15-lipoxygenase, cyclooxygenases, and pro-inflammatory cytokines;European Journal of Medicinal Chemistry;2023-08
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3