Synthesis and biological evaluation of thio-benzodiazepines as novel small molecule inhibitors of the p53–MDM2 protein–protein interaction-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of thio-benzodiazepines as novel small molecule inhibitors of the p53–MDM2 protein–protein interaction

Published:2011-11 Issue:11 Volume:46 Page:5654-5661
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Zhuang Chunlin,Miao Zhenyuan,Zhu Lingjian,Zhang Yongqiang,Guo Zizhao,Yao Jianzhong,Dong Guoqiang,Wang Shengzheng,Liu Yang,Chen Hai,Sheng Chunquan,Zhang Wannian

Funder

Science and Technology of Shanghai

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference22 articles.

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4. Inhibiting the p53-MDM2 interaction: an important target for cancer therapy;Chene;Nat. Rev. Cancer,2003

5. p53 Activation by small molecules: application in oncology;Vassilev;J. Med. Chem.,2005

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