Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma-Reference-Cited by-同舟云学术

Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma

Published:2016-08 Issue: Volume:118 Page:47-63
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Sestito Simona,Daniele Simona,Nesi Giulia,Zappelli Elisa,Di Maio Danilo,Marinelli Luciana,Digiacomo Maria,Lapucci Annalina,Martini Claudia,Novellino Ettore,Rapposelli Simona^ORCID

Funder

FIRB

International Society for Drug Development

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference53 articles.

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4. PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE;Pinner;Nat. Cell Biol.,2008

5. Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival;Flynn;Curr. Biol.,2000

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