Novel sulfonyl(thio)urea derivatives act efficiently both as insulin secretagogues and as insulinomimetic compounds

Author:

Mascarello Alessandra,Silva Frederico Marisa Jádna,Gomes Castro Alisson Jhonathan,Mendes Camila P.,Dutra Márcio Ferreira,Woehl Viviane Mara,Yunes Rosendo Augusto,Mena Barreto Silva Fátima Regina,Nunes Ricardo José

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico-Brasil (CNPq)

Coordenação de Pessoal de Nível Superior (CAPES-PPG-Bioquímica)

Fundação de Amparo à Pesquisa do Estado de Santa Catarina (FAPESC)

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference43 articles.

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3. Interaction of the sulfonylthiourea HMR 1833 with sulfonylurea receptors and recombinant ATP-sensitive K+ channels: comparison with glibenclamide;Russ;J. Pharmacol. Exp. Ther.,2001

4. Investigation of structure–activity relationships in a series of glibenclamide analogues;Yuriev;Eur. J. Med. Chem.,2004

5. Synthesis and evaluation of a glibenclamide glucose-conjugate: a potential new lead compound for substituted glibenclamide derivatives as islet imaging agents;Schneider;Regul. Pept.,2007

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