“Hit” to lead optimization and chemoinformatic studies for a new series of Autotaxin inhibitors-Reference-Cited by-同舟云学术

“Hit” to lead optimization and chemoinformatic studies for a new series of Autotaxin inhibitors

Published:2023-03 Issue: Volume:249 Page:115130
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Stylianaki Elli-Anna,Magkrioti Christiana,Ladopoulou Eleni M.,Papavasileiou Konstantinos D.,Lagarias Panagiotis,Melagraki Georgia,Samiotaki Martina,Panayotou George,Dedos Skarlatos G.,Afantitis Antreas,Aidinis Vassilis,Matralis Alexios N.^ORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference62 articles.

1. Autotaxin and chronic inflammatory diseases;Magkrioti;J. Autoimmun.,2019

2. Autotaxin, a secreted lysophospholipase D, as a promising therapeutic target in chronic inflammation and cancer;Barbayianni;Prog. Lipid Res.,2015

3. Deregulated lysophosphatidic acid metabolism and signaling in liver cancer;Kaffe;Cancers,2019

4. ATX expression and LPA signaling are vital for the development of the nervous system;Photopoulou;Dev. Biol.,2010

5. Pirfenidone in patients with with idiopathic pulmonary fibrosis (CAPACITY): two randomized trials;Noble;Lancet,2011

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