Structure-based discovery of novel α-aminoketone derivatives as dual p53-MDM2/MDMX inhibitors for the treatment of cancer-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Structure-based discovery of novel α-aminoketone derivatives as dual p53-MDM2/MDMX inhibitors for the treatment of cancer

Published:2023-04 Issue: Volume:252 Page:115282
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Luo Hui-juan,Si Dong-juan,Sun Xin-jie,Wang Meng-yun,Yang Yao-bin,Wang Bo,Wen Hong-mei,Li Wei,Liu Jian

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference41 articles.

1. Tumor suppressor p53: biology, signaling pathways, and therapeutic targeting;Hernández Borrero;Biochim. Biophys. Acta, Rev. Cancer,2021

2. p53 and tumor suppression: it takes a network;Boutelle;Trends Cell Biol.,2021

3. Mdm2 and MdmX: partners in p53 destruction;Manfredi;Cancer Res.,2021

4. The MDM2/MDMX/p53 axis in the adaptive stress response;Wang;Transl. Cancer Res.,2020

5. Spontaneous and inherited TP53 genetic alterations;Levine;Oncogene,2021

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Cellular, Structural Basis, and Recent Progress for Targeting Murine Double Minute X (MDMX) in Tumors;Journal of Medicinal Chemistry;2024-08-26

2. Visible-Light-Promoted Enantioselective Acylation and Alkylation of Aldimines Enabled by 9-Fluorenone Electron-Shuttle Catalysis;Journal of the American Chemical Society;2024-07-09

3. Novel 9-Methylanthracene Derivatives as p53 Activators for the Treatment of Glioblastoma Multiforme;Molecules;2024-05-19

4. Quinazoline sulfonamide derivatives targeting MicroRNA-34a/MDM4/p53 apoptotic axis with radiosensitizing activity;Future Medicinal Chemistry;2024-04-25

5. Synthesis and biological evaluation of 4-imidazolidinone–containing compounds as potent inhibitors of the MDM2/p53 interaction;European Journal of Medicinal Chemistry;2024-04

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3