A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B-Reference-Cited by-同舟云学术

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A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B

Published:2023-09 Issue: Volume:257 Page:115485
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Chen Wuhong,Gong Ying,Long Guozhang,Wang Xinran,Yang Yurong,Liu Jia,Li Heng,Tong Xiankun,Zhao Qiliang,Yang Li,Zuo Jianping,Hu Youhong

Funder

National Natural Science Foundation of China

Shenzhen Science and Technology Innovation Program

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference33 articles.

1. The 2019 EASL-AASLD HBV Treatment Endpoints Conference Faculty, et al. Guidance for Design and Endpoints of Clinical Trials in Chronic Hepatitis B—report From the 2019 EASL-AASLD HBV Treatment Endpoints Conference;Cornberg;Hepatology,2020

2. Hepatitis B surface antigen seroclearance: immune mechanisms, clinical impact, importance for drug development;Tout;J. Hepatol.,2020

3. Therapeutic strategies for hepatitis B virus infection: towards a cure;Fanning;Nat. Rev. Drug Discov.,2019

4. RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg;Wooddell;Sci. Transl. Med.,2017

5. Factors associated with rates of HBsAg seroclearance in adults with chronic HBV infection: a systematic review and meta-analysis;Yeo;Gastroenterology,2019

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Classifying hepatitis B therapies with insights from covalently closed circular DNA dynamics;Virologica Sinica;2023-12

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