Discovery of 6-aryl-2-(3,4,5-trimethoxyphenyl)thiazole[3,2-b][1,2,4]triazoles as potent tubulin polymerization inhibitors
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference35 articles.
1. Microtubules as a target for anticancer drugs;Jordan;Nat. Rev. Cancer,2004
2. Structure-function analysis of yeast tubulin;Luchniak;Methods Cell Biol.,2013
3. Targeting mitosis in cancer: emerging strategies;Dominguez-Brauer;Mol. Cell.,2015
4. A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs;Prota;Proc. Natl. Acad. Sci. USA,2014
5. Natural anti-tubulin agents: importance of 3,4,5-trimethoxyphenyl fragment;Negi;Bioorg. Med. Chem.,2015
Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Discovery of novel coumarin-based derivatives as inhibitors of tubulin polymerization targeting the colchicine binding site with potent anti-gastric cancer activities;European Journal of Medicinal Chemistry;2024-02
2. Synthesis and biological evaluation of structurally diverse 6-aryl-3-aroyl-indole analogues as inhibitors of tubulin polymerization;European Journal of Medicinal Chemistry;2024-01
3. Modulation of taxane binding to tubulin curved and straight conformations by systematic 3′N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potency;European Journal of Medicinal Chemistry;2023-11
4. The trimethoxyphenyl (TMP) functional group: a versatile pharmacophore;Medicinal Chemistry Research;2023-10-16
5. Design and Synthesis of New 4-(3,4,5-Trimethoxyphenyl)Thiazole–Pyrimidine Derivatives as Potential Antiproliferative Agents;Medicina;2023-06-02
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3