Discovery of 6-aryl-2-(3,4,5-trimethoxyphenyl)thiazole[3,2-b][1,2,4]triazoles as potent tubulin polymerization inhibitors
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference35 articles.
1. Microtubules as a target for anticancer drugs;Jordan;Nat. Rev. Cancer,2004
2. Structure-function analysis of yeast tubulin;Luchniak;Methods Cell Biol.,2013
3. Targeting mitosis in cancer: emerging strategies;Dominguez-Brauer;Mol. Cell.,2015
4. A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs;Prota;Proc. Natl. Acad. Sci. USA,2014
5. Natural anti-tubulin agents: importance of 3,4,5-trimethoxyphenyl fragment;Negi;Bioorg. Med. Chem.,2015
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