Development of novel pyrazole, imidazo[1,2-b]pyrazole, and pyrazolo[1,5-a]pyrimidine derivatives as a new class of COX-2 inhibitors with immunomodulatory potential

Author:

Ayman Radwa,Abusaif Moustafa S.,Radwan A.M.,Elmetwally Amira M.,Ragab AhmedORCID

Funder

Ministry of Education - Singapore

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference68 articles.

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3. Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation;Vane;Proc. Nad. Acad. Sci. USA,1994

4. Evolution of nonsteroidal anti-inflammatory drugs (NSAIDs): cyclooxygenase (COX) inhibition and beyond;Rao;J. Pharm. Pharmaceut. Sci.,1997

5. Modulation of enzyme-catalyzed synthesis of prostaglandins by components contained in kidney microsomal preparations;Bai;Molecules,2022

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