Design, synthesis and anti-AD effects of dual inhibitor targeting glutaminyl cyclase/GSK-3β-Reference-Cited by-同舟云学术

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Design, synthesis and anti-AD effects of dual inhibitor targeting glutaminyl cyclase/GSK-3β

Published:2023-02 Issue: Volume:248 Page:115089
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Xie Yazhou,Chen Chen,Lin Shujing,Yu Xi,Ye Shuixian,Chen Xiaojie,Ouyang Na,Xiong Wei,Li Chenyang,Xu Chenshu,Song Guoli,Wu Haiqiang

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference24 articles.

1. Repurposing FDA-approved compounds for the discovery of glutaminyl cyclase inhibitors as drugs against Alzheimer's disease;Xu;Chem. Open,2021

2. Molecular mechanisms of ER stress and UPR in the pathogenesis of Alzheimer's disease;Uddin;Mol. Neurobiol.,2020

3. Focusing the amyloid cascade hypothesis on N-truncated Abeta peptides as drug targets against Alzheimer's disease;Bayer;Acta Neuropathol.,2014

4. Differential toxicity, conformation and morphology of typical initial aggregation states of Abeta1-42 and Abetapy3-42 beta-amyloids;Galante;Int. J. Biochem. Cell Biol.,2012

5. Pyroglutamate formation influences solubility and amyloidogenicity of amyloid peptides;Schlenzig;Biochemistry,2009

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of potential scaffolds for glutaminyl cyclase inhibitors: Virtual screening, synthesis, and evaluation;Bioorganic & Medicinal Chemistry;2024-01

2. Targeting protein kinases for the treatment of Alzheimer's disease: Recent progress and future perspectives;European Journal of Medicinal Chemistry;2023-12

3. Therapeutic potential of glutaminyl cyclases: Current status and emerging trends;Drug Discovery Today;2023-10

4. Development of lactoferrin-coated multifunctional copolymer micelles to cross the blood-brain barrier;Drug Delivery and Translational Research;2023-09-18

5. Development and evolution of human glutaminyl cyclase inhibitors (QCIs): an alternative promising approach for disease-modifying treatment of Alzheimer's disease;Frontiers in Aging Neuroscience;2023-08-03

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