Machine learning- and structure-based discovery of a novel chemotype as FXR agonists for potential treatment of nonalcoholic fatty liver disease-Reference-Cited by-同舟云学术

Machine learning- and structure-based discovery of a novel chemotype as FXR agonists for potential treatment of nonalcoholic fatty liver disease

Published:2023-04 Issue: Volume:252 Page:115307
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Qin Tong^ORCID,Gao Xuefeng,Lei Lei,Feng Jing,Zhang Wenxuan,Hu Yuhua,Shen Zhufang,Liu Zhenming^ORCID,Huan Yi,Wu Song^ORCID,Xia Jie^ORCID,Zhang Liangren

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference73 articles.

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5. A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis;Goodwin;Mol. Cell,2000

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