Discovery of Ibrutinib-based BTK PROTACs with in vivo anti-inflammatory efficacy by inhibiting NF-κB activation
Author:
Funder
National Natural Science Foundation of China
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference34 articles.
1. Inflammasome-derived exosomes activate NF-κB signaling in macrophages;Zhang;J. Proteome Res.,2017
2. NF-κB signaling in inflammation;Liu;Signal Transduct. Targeted Ther.,2017
3. Nuclear factor-κB is activated in alveolar macrophages from patients with acute respiratory distress syndrome;Schwartz;Crit. Care Med.,1996
4. Immune deficiency or hyperactivity-Nf-κb illuminates autoimmunity;Pai;J. Autoimmun.,2008
5. STAT3 activation in combination with NF-KappaB inhibition induces tolerogenic dendritic cells with high therapeutic potential to attenuate collagen-induced arthritis;Prado;Journal of Immunology Research,2019
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