Isoxazolidinyl polycyclic aromatic hydrocarbons as DNA-intercalating antitumor agents

Author:

Rescifina Antonio,Chiacchio Ugo,Corsaro Antonino,Piperno Anna,Romeo Roberto

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference40 articles.

1. Structural considerations in the interaction of deoxyribonucleic acid and acridines;Lerman;J. Mol. Biol.,1961

2. Interactions of anilinoacridines with nucleic acids: effects of substituent modifications on DNA-binding properties;Wadkins;Biochemistry,1986

3. DNA-intercalating ligands as anti-cancer drugs: prospects for future design;Denny;Anticancer Drug Des.,1980

4. Intercalation mechanisms with ds-DNA: binding modes and energy contributions with benzene, naphthalene, quinoline and indole derivatives including some antimalarials;Sartorius;J. Chem. Soc. Perkin Trans.,1997

5. Potential antitumor agents. 56. ‘Minimal’ DNA-intercalating ligands as antitumor drugs: phenylquinoline-8-carboxamides;Atwell;J. Med. Chem.,1988

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