New, highly potent and non-toxic, chromone inhibitors of the human breast cancer resistance protein ABCG2

Author:

Pires Amanda do Rocio Andrade,Lecerf-Schmidt Florine,Guragossian Nathalie,Pazinato Jaqueline,Gozzi Gustavo Jabor,Winter Evelyn,Valdameri Glaucio,Veale AlexanderORCID,Boumendjel Ahcène,Di Pietro Attilio,Pérès Basile

Funder

ANR Labex Arcane

Ligue Nationale contre le Cancer

CNPq

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference27 articles.

1. The biochemistry of P-glycoprotein-mediated multidrug resistance;Endicott;Annu. Rev. Biochem.,1989

2. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line;Cole;Science,1992

3. A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance;Allikmets;Cancer Res.,1998

4. A multidrug resistance transporter from human MCF-7 breast cancer cells;Doyle;Proc. Natl. Acad. Sci. U. S. A.,1998

5. Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes;Miyake;Cancer Res.,1999

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